Hi! We’re given the following scenario and I just need help answering some of the questions.
Ã¢Ouch,Ã¢ said Kyle, drinking a glass of soda, Ã¢my stomach hurts.Ã¢
Concerned, his girlfriend Wendy, asked, Ã¢What have you been eating? Did you go to that cheap wing
place again and order the nuclear wings? Because, if you did, itÃ¢s your own fault!Ã¢
Ã¢No,Ã¢ said Kyle, Ã¢I just took some aspirin for my headache. We were up late practicing last night and I
had a slight headache, probably from sleep deprivation. I took some aspirin from the bottle in your
Wendy knew from experience that aspirin could hurt your stomach, especially if you took it often or had
an ulcer or other kind of stomach problem. But Kyle seemed fine, he is a healthy 20-year old with no
health problems that she knew of.
Ã¢Well, how many did you take?Ã¢ she asked.
Ã¢The normal amount, four,Ã¢ replied Kyle.
Ã¢But thatÃ¢s TWICE the normal dosage!Ã¢
Ã¢I always take four at home. ThatÃ¢s how many I need to get rid of my headaches and IÃ¢ve never had my
stomach hurt like this,Ã¢ said Kyle.
Hmmm thought Wendy, I wonder why the four aspirin he takes at home donÃ¢t upset his stomach like the
ones here do? She asked, Ã¢What brand do you take at home?Ã¢ She knew that she purchased BayerÃÂ®
aspirin, had used the same thing for years without any side effects.
Ã¢Oh, I donÃ¢t know, Ã¢ replied Kyle, Ã¢something my roommate Stan buys over the Internet. From some site
that has cheap drugs, www.cheapdrugs.com, I think. He can get, like, a thousand aspirin for only $3.50,
including shipping and handling. What a deal. We started out taking 2 pills like the label says, but that
dose never seemed to work, so we started doubling it. My stomach never hurt like this. Maybe thereÃ¢s
something in them to prevent stomach pain, like an antacid-aspirin hybrid?Ã¢
Wendy had taken some chemistry classes during her first year of college and she was doubtful that KyleÃ¢s
Internet aspirin contained both antacid and aspirin. She thought that maybe something else was up. If
only she could get access to the chemistry laboratories, maybe she could find out what these Internet
aspirin contained. SAFETY CONCERNS
This laboratory exercise uses sodium hydroxide (NaOH), which is corrosive and an irritant. Handle with
care, and wash any affected areas with copious amounts of water.
This laboratory exercise uses benzophenone (in KyleÃ¢s aspirin), which is an irritant and flammable.
Handle with care and avoid prolonged contact.
This laboratory exercise uses acetylsalicylic acid (aspirin), which is an irritant, flammable and allergenic.
Handle with care and avoid prolonged contact. PRELAB ASSIGNMENT
Type your responses to questions 1-5 and turn into the teaching
assistant upon entering the lab. The procedure in your notebook will
be checked for completeness. You must have a complete research
plan to enter lab.
1. After reading this, do you think that you can help Wendy
determine why Kyle needs a larger dose of his brand of aspirin?
2. Why do you believe it took a larger dose of Internet aspirin to cure
KyleÃ¢s headaches? Formulate this into a hypothesis that can be
3. How can you test your hypothesis?
4. What information do you need before you can devise a method for
testing your hypothesis?
5. What control experiments would you need to perform?
6. Using the list of chemicals and equipment provided, write a
detailed procedure in your notebook describing the experiment(s)
you will conduct. You will have the following
available in the laboratory:
Ã¢Â¢ Aspirin tablets (with a
known amount of
Ã¢Â¢ A sample of KyleÃ¢s
Ã¢Â¢ Acetylsalicylic acid
Ã¢Â¢ Standardized NaOH
Ã¢Â¢ pH meters
Ã¢Â¢ methanol (used to
dissolve the tablets)
Ã¢Â¢ mortar & pestle (to
Ã¢Â¢ burets & buret clamps
Ã¢Â¢ stir plates & stir bars
Ã¢Â¢ glassware IN LAB