(a) Comment on the significance of each of the following points with respect to Desferrioxamine B, in terms of its suitability as a drug to treat…

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(a)   Comment on the significance of each of the following points with respect to Desferrioxamine B, in terms of its suitability as a drug to treat iron overload.

(i)       The stability constant for this ligand with Fe(III) is 1030.6. You should also suggest whether the value is high or low, and explain why this might be the case.

(ii)     The pKa values of hydroxylamine groups in the absence of metals are around 8-9.

(iii)   E˜ (Fe3 | Fe2) for the complex is −0.45 V 

 
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